Sardiello Lab

Marco Sardiello, PhD

Our lab is primarily focused on medical genetics. Building on the foundation established by the Human Genome Project, we continuously work to characterize un-annotated genes and proteins associated with hereditary disorders.

Lysosomes are a central part of our research. By characterizing lysosomal proteins, we aim to find ways to combat lysosomal storage neurodegenerative diseases. In 2009, Sardiello characterized TFEB (transcription factor EB) in a groundbreaking study that refined the role of lysosomes. Since then, the Sardiello lab has been dedicated to understanding lysosomal proteins to treat or cure neuronal ceroid lipofuscinoses, a specific type of lysosomal storage disease.

Translational medicine is one of our top priorities. We believe strongly in bench-to-bedside approaches and work diligently to realize this ideal. Our research not only focuses on characterizing and discovering new scientific concepts but also on delivering the benefits of our discoveries to the patients who need them. The Sardiello lab is committed to making a difference.

Principal investigator

Our team

Affiliated faculty

Personnel


Recent publications